Haematological malignancies generally have a multitude of aberrations across the Genome. These include fusion genes, copy number alterations and somatic mutations. However, no one technology can efficiently assess all of these aberration types, making the profiling of haematological malignancies labour and time-intensive.

The genetic complexity of cancer cells in haematological malignancies requires a thorough approach to detect relevant changes. The identification of copy number losses and gains, LOH, cnLOH, clonal heterogeneity, and ploidy status, as well as mosaicism, are all critical for evaluating blood cancer samples to discover new biomarkers.

Indalo Bio can help you successfully test for haematological malignancies to provide your patients with an accurate clinical diagnosis.

SIMPLIFYING HAEMATOLOGICAL MALIGNANCY PROFILING

DIFFICULT-TO-SEQUENCE GENES ARE COVERED WITH HIGH QUALITY ENABLING TRUE DIAGNOSTIC IMPACT IN EVEN THE MOST CHALLENGING PATIENT CASES.

An accurate genetic diagnosis is vital to confirm the diagnosis of certain haematological malignancies. Genetic tests can also help find the optimal treatment plan for patients. Establishing the underlying inheritance pattern and genetic defect pattern further allows family member testing to identify at-risk relatives. A genetic diagnosis can also assist in family planning.

Our panels include:

  • Genes based on curated gene reviews
  • Variant databases (HGMD and ClinVar)
  • Customer requests
  • The most recent literature
  • Maximized diagnostic yield
  • Enhanced clinical utility
  • Empowered differential diagnosis
  • Analytically validated up-to-date genes across all panels.

INDALO BIO OFFERS THE FOLLOWING HAEMATOLOGY PANELS:

  • Anemia Panel
  • Bleeding Disorder/Coagulopathy Panel
  • Bone Marrow Failure Syndrome Panel
  • Coagulation Factor Deficiency Panel
  • Comprehensive Hematology and Hereditary Cancer Panel
  • Comprehensive Hematology Panel
  • Congenital Neutropenia Panel
  • Diamond-Blackfan Anemia Panel
  • Dyskeratosis Congenita Panel
  • Fanconi Anemia Panel
  • Hemophagocytic Lymphohistiocytosis Panel
  • Hereditary Leukemia Panel
  • Hermansky-Pudlak Syndrome Panel
  • Platelet Function Disorder Panel
  • Red Blood Cell Membrane Disorder Panel
  • Thrombocytopenia Panel
Find Out More

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Next generation cytogenetics: genome-imaging enables comprehensive structural variant detection for 100 constitutional chromosomal aberrations in 85 samples

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Haplotype-resolved diverse human genomes and integrated analysis of structural variation

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Characterization of an unbalanced translocation causing 3q28qter duplication and 10q26.2qter deletion in a patient with global developmental delay and self-injury

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Beginner’s Guide to Optical Genome Mapping: The Key to Structural Variation Detection

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From Data to Discovery: Tools to identify the pathogenic structural variant in patients with genetic disease

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Resolving Complex Haplotypes Implicated in Alzheimer’s and Other Neurodegenerative Diseases

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Optical Mapping in Rare Genetic Disease Diagnosis

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HOW TO GET STARTED

STEP 1

Contact Us or Book Your Slot Online

STEP 2

Provide Us with Your Sample

STEP 3

Samples are Returned